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What is Oxycontin 80mg ? This drug is used to treat chronic pain that is severe (such as due to cancer). Oxycodone is an opioid analgesic, which means it relieves pain. It alters the way your body perceives and responds to pain by acting on the brain. Only use the higher doses of this drug (more than 40 mg per tablet) if you have been taking moderate to large dosages of an opioid pain medication on a regular basis. If taken by someone who hasn't been using opioids consistently, these strengths can lead to overdose (and perhaps death). Use the extended-release type of oxycodone for pain that is minor or will go away in a few days, not for chronic pain . What are the side-effects of Oxycontin 80mg ? l It's possible that you'll experience nausea, vomiting, constipation, dry mouth, ...